Paras NobleCleav® Technology
NobleCleav® - An Innovative Technology
For Production of Difficult Therapeutic Proteins
NobleCleav® Technology
NobleCleav® is a proprietary technology for efficient processing of recombinant therapeutic peptides and therapeutic proteins. The technology facilitates high level production of authentic biologics by combining high specificity and activity of processing. The technology significantly reduces wastage of the biologics during processing and thereby increases yields and significantly brings down the cost of production of biologics.
Technology Approach
Paras Biopharmaceuticals technological approach is solely focused on achieving a successful product development. As a result, there are three main features that drive our technological innovations:
- Work is only performed in the laboratory on processes which can be successfully and economically scaled up. An understanding of industrial scale production approach eliminates many unnecessary steps which normally become bottlenecked in an ordinary approach.
- We focus and utilize only the most efficient process steps to achieve success whilst optimizing each step in relation to customer needs, keeping quality in mind.
- We successfully combine scientific expertise and proven industrial forming a solid foundation which allows economic product and process developments take center stage.
Technology Features
- Optimum plasmid copy number
- Includes vectors that are most suitable for E. Coli expression systems
- Incorporates tightly controlled protein expression
- Enables high expression yields, even for difficult and challenging proteins
- Cleavage generates authentic N and C- terminus
- Incorporates gene construct with Paras Propriety Partner PPP and spacers suitable for high expression
NobleCleav® Technology allows:
- Innovative technology developed by Paras Biopharmaceuticals successfully results in quality biopharmaceutical products with comparative biological activity of the product.
- Platform enables new and innovative ways employing combined unique expertise to perform cleavage of proteins with a fusion partner.
- Increased specificity and activity of processing.
- Decreased wastage and therefore decreased production costs.
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