Research & Development - Overview

Paras Biopharmaceuticals Finland Oy is driven by the outstanding technology skills and scientific expertise of well-known academics and technological experts. The team of scientific expertise together with technological entrepreneurs has already successfully created significant innovations in biopharma technology.

Paras Biopharmaceuticals Finland Oy extends its expertise, core competence and skills in the development of recombinant DNA technologies to service its client's need. Paras Biopharmaceuticals Finland Oy has achieved remarkable success in developing core platform technologies.

Clone Development

Paras Biopharmaceuticals Finland Oy clone development is based on the most advanced and latest scientific and technological knowledge in the utilization of Codons, Sequence optimization plasmid selection, Optimal strain selection, bioinformatics, Oligo-synthesis, Gene assembly, Cloning, and The sequencing and Final product confirmations.

• Codon optimization
• Detailed report on codon optimization
• Plasmid selection
• Achieving highest titers
• Documentation on clone development
• Sequences and product confirmations
  

Upstream Process Development

A robust upstream process development is critical in achieving the highest production efficiencies. This facilitates the highest possible economic value and defines the feasibility of the commercial scale.

The Paras team is highly experienced to provide exceptional process development to achieve the highest levels of production.

• Selection and development of media in laboratory scale.
• Development of the most suitable process parameters for scale-up and large scale production.
• Achieving the highest expression levels and production on the market today.

Purification Development

Paras Biopharmaceuticals Finland Oy utilizes the most advanced understanding of protein purification, thereby achieving the highest purification efficiencies and quality of the product in the market today. Achieving the highest yields in protein purification is very difficult, time consuming and very expensive. At Paras Biopharmaceuticals Finland Oy, we know this all too well and so our team utilizes the experience of many industrial biological techniques to achieve the highest purification efficiencies in the most economical manner possible.

• Resin screening for the highest yields.
• Minimize aggregation concepts in purification.
• Scale-up and scale-down approaches in determining the most economic outcome.
• Achieve the highest purification efficiencies.

Technology Package

Tech Package includes:
Reports on cloning, cell line (clone) development, media optimization, fermentation, scale-up, product optimization, purification development, analytical methods (detailed report with MS/ proteomics) and product API characterization.